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Follow the link for more information. The two sequences meet at the end of the film, producing one complete and cohesive narrative. European theaters starting in October. As the sequence plays backwards the photo reverts to its undeveloped state, entering the camera before the man is shot in the head. The black and white sequences begin with Leonard Shelby, an insurance investigator, in a motel room speaking to an unseen and unknown caller.

Leonard explains that he killed the attacker who raped and strangled his wife, but a second clubbed him and escaped. The police did not accept that there was a second attacker, but Leonard believes the attacker’s name is John or James, with a last name starting with G. So, Leonard conducts his own investigation using a convoluted system of notes, Polaroid photos, and tattoos. From his occupation in the insurance industry, Leonard recalls a fellow anterograde amnesiac, Sammy Jankis. However, Sammy continues to administer the injections, and his wife falls into a fatal coma.

The color sequences are shown reverse-chronologically. Finding a note in his clothes, he meets Natalie, a bartender who resents Leonard because he wears the clothes and drives the car of her boyfriend, Jimmy Grantz. After understanding Leonard’s condition, she uses it to get Leonard to drive a man named Dodd out of town and offers to run the license plate as a favor. Meanwhile, Leonard meets with a contact, Teddy, who helps with Dodd, but warns about Natalie.

However, a photograph causes Leonard not to trust Teddy. Natalie provides Leonard with the driver’s license for a John Edward Gammell, Teddy’s full name. Confirming Leonard’s information on “John G” and his warnings, Leonard drives Teddy to an abandoned building, leading to the opening, where he shoots him. In the final black-and-white sequence, prompted by the caller, Leonard meets with Teddy, an undercover officer, who has found Leonard’s “John G,” Jimmy, and directs Leonard to the abandoned building. When Jimmy arrives, Leonard strangles him fatally and takes a Polaroid photo of the body. As the photo develops, the black-and-white transitions to the final color sequence.